"Krita." I am hearing some good things but haven't had a chance to run it yet.
Krita teams original goals were:
- Based on KOM
- XML-based File formats
- RGB support
- CYMK support
- Compatiblity with Gimp plugins
- Scriptable with Python
- Based on Image Magic Core
- Multi-threading
- 16bit channel images
So far 1.4 supports:
- RGB
- Gray
- filters
- xcf,psd,png,tiff, jpeg....
- Selections
- Many tools
- Layers
- Tablet support
- Color management
The next release will have:
- CMYK, RGB, GRAY,XYZ, Watercolors
- 8,16,32 bits/channel
- OpenEXR support
- More color management
- Scripting
- A full dcop interface
- Channel separations
- Adjustment with curves
- Many more filters